Sentence examples for be generated by epigenetic from inspiring English sources
Patient-specific iPSCs can be generated by epigenetic reprogramming of various adult cell types such as skin fibroblasts and blood mononuclear cells and just like embryonic stem cells (ESCs), self-renew indefinitely and retain the potential to give rise to all cell types in the human body (Takahashi et al, 2007).
Such qualitative variabilities within the same cell population are generated by epigenetic commitment of cells to different fates (e.g., proliferation versus differentiation) as well as by genetic alterations (Fig. 1b) as in cancer [ 13, 14].
Thus, this effect had to be generated by the gametic transfer of epigenetic information.
Recent studies have suggested that differentially spliced forms of many SMAD family members are generated by genetic or epigenetic inactivation and may represent an important step in neoplastic transformation [ 26– 28].
This very particular model system was generated by repeated cycles of adhesion/de-adhesion, which in turn led to epigenetic reprogramming 31.
