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This sort of dynamical systems can be generated by differential equations with both non-autonomous deterministic and stochastic external terms.
Thus, SRF1 is unusual as the RLK and RLP versions of SRF1 appear to be generated by differential splicing.
In fact, at least four different Her4 variants (JM-a/CYT1, JM-a/CYT2, JM-b/CYT1, and JM-b/CYT2) can be generated by differential Her4 mRNA splicing.
As distinct EGFR signal outputs may be generated by differential ligand activation [ 64], it is possible that anabolic EGFR activities could be mediated by ligands other than EGF or TGF-α; alternately, anabolic vs. catabolic EGFR activities in articular cartilage could be related to differences in the timing or level of EGFR activation achieved in in vitro studies vs. our in vivo studies.
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Soluble forms of CD137 (sCD137) are generated by differential splicing and may limit DC activation [22], [23].
The Stau2 gene expresses four protein isoforms of 62, 59, 56 and 52 kDa that are generated by differential splicing (Fig. 1) [7].
However alternative isoforms of bee neurexin I are generated by differential use of 12 splice sites, mostly located in regions encoding LNS subdomains.
Drug response signatures were generated by differential analysis, which compared the expression profile of each treated cell line with that of the untreated cell line by measuring the fold-change (treated/untreated) of each probe set.
Molecular diversity of AMPA/KA and NMDA receptors under physiological or pathological conditions is generated by differential spatial-temporal patterns of GluR expression, by alternative RNA splicing and editing and by targeting and trafficking of receptor subunits at dendritic spines [22].
These transcripts are generated by differential selection of splice sites during pre-mRNA processing.
Four isoforms are generated by differential splicing due to the use of alternative splice acceptor sites for exon 1.
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