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For instance, in theory, a similar inward bias may also be generated by biased apical expansion and/or basal constriction of NR epithelium 52– 54, while some resistance of NR's basement membrane to tangential expansion also favors apically convex curving.
This reinforces the strong link between recombination and CGIs in dog, indicating that new CGIs in the dog genome are likely to be generated by biased substitution patterns caused by gBGC.
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Therefore, relative risks close to the null are more likely to be generated by bias than by more extreme results.
Although speculative, such frequent nonrandom allelic replacements could be generated by biases at the level of recombination by, for example, repeats.
While spatial oscillators can be generated by biasing of an oscillator circuit with (not too strongly) diffusible elements, having highly diffusible elements in the circuit generating oscillations result in complete global coupling.
11 40 41 This similarity provides reassuring evidence that offspring BMI serves as a useful indicator of own BMI when studying these associations, as it is difficult to see how such a pattern could be generated by bias.
The problem is that the behavior is generated by biases that function almost entirely at a subintentional level (Sperber, 1997).
Since the observation that highly expressed genes are compact also can be generated by the transcription-associated non-adaptive deletion bias, the third hypothesis be called mutational bias hypothesis has been proposed, which suggests that highly expressed genes tend to localize in chromosomal regions with high deletion rates, or that there is a transcription-associated deletion bias[ 2, 8].
The observation that highly expressed genes are compact also can be generated by the transcription-associated non-adaptive deletion bias.
Such an initiative would eliminate, or at least minimize, the biases that can be generated by analyzing data using multiple methodologies.
Cheung et al. [ 13] studied ChIP data from Illumina's Genome Analyser and found three types of systematic sequencing errors: those caused by GC content, mappability of sequencing reads, and regional biases that might be generated by local structure.
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