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Isolated Josephin species could be generated by alternative splicing or proteolysis.
In total, three sets of different mRNAs could be generated by alternative splicing for these Ugt5 genes.
In certain species cytosolic PrP can be generated by alternative initiation of translation, which produces PrP molecules with short signal peptides unable to negotiate entry into the ER [53], [54].
Several CD45 isoforms can be generated by alternative splicing of exons 4(A), 5(B) and 6(C) leading to change in the extracellular domain of the molecule [16].
Binding, on the other hand, mainly requires that the protein has a surface with appropriate properties as defined by electrostatic-, hydrophobic- and van der Waals-interactions, and such a surface may be generated by alternative structures.
Variants of a protein can also be generated by alternative splicing of mRNA transcripts.
Similar(42)
Evidence suggests that human endogenous sRAGE is generated by alternative splicing of RAGE mRNA, or alternatively, by proteolytic cleavage from membranous RAGE [ 23].
We have found that Insig1 mRNAs are generated by alternative cleavage and polyadenylation, resulting in specific isoform mRNA species.
Le, H. T., Sorrell, A. M. & Siddle, K. Two isoforms of the mRNA binding protein IGF2BP2 are generated by alternative translational initiation.
In mammals, it has been demonstrated that at least four forms of Pax-6 are generated by alternative splicing and sumoylation.
In humans, there are two major c-mpl molecules, MplP and MplK, which are generated by alternative splicing.
More suggestions(16)
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