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Oxygen free radicals can also be generated by activated microglia and infiltrating leukocytes via the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase pathway following reperfusion.
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In addition, during inflammatory processes more ROS are generated by activated mast cells, macrophages, eosinophils, and neutrophils that have the potential to injure airway lining cells [6], [7].
In the progress of inflammation, NO is generated by activated inducible iNOS, and participated in the innate response along with other macrophage mediators in many mammal.
These most likely represent endothelial microparticles which are generated by activated endothelial cells and are increased in the serum of patients with SSc.
Furthermore, a large amount of plasma cells infiltrating the synovial tissue appeared to be generated by locally activated B cells [ 55].
Such a difference could be generated by variability in the level of activated NF-κB infectedted cells from different breeds, or a difference in a parasite-dependent mechanism that controls NF-κB target gene expression.
Such cytokines could be generated by the innate immune response in the retina; the number of activated T cell infiltration was minimal during early EAU.
A fROI map was generated by conjoining activated regions identified in the above spatial extent analyses across the control group and the PD ON and OFF conditions.
The masses of the peptide fragments are measured and fragmentation of the peptide is generated by collisionally activated dissociation (Fig. 6A).
These iTSCM cells are generated by coculturing of activated T cells with Notch ligand-expressing stromal cells.
HMELR cells were generated (by addition of activated H-RAS) and donated by Dr. Yashaswi Shrestha (Broad Institute Cancer Program).
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