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This may potentially be to permit passive DNA demethylation [ 85] and cell cycling will certainly be necessary if new cell types need to be generated and expanded from just a few reprogrammed somatic cells.
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In this study, the continuous change in the critical radius is theoretically demonstrated under atmospheric pressure while bubbles are generated and expanded by the decomposition of a chemical blowing agent.
Murine WT- and MRL-MSCs were generated and expanded from C57BL6 and MRL/MpJ strains, respectively, as described [ 5, 10].
Stephen et al. studied the evolution of UCEs in several vertebrate genomes and found that they were generated and expanded on a large scale during tetrapod evolution [ 15].
Δ3 4-fibroblasts were generated and expanded from a skin punch biopsy of a classic RTT patient at The Hospital for Sick Children, Canada, under the approval of the SickKids Research Ethics Board.
An enormous amount of biological data are generated and continues to expand dramatically, with the completion of Human Genome Project and the introduction of the next-generation sequencing.
Mol blocks were converted to CDK structures, fingerprints were generated and the fingerprint was then expanded and appended to the structural information.
Due to quantity times quality nonlinear terms inherent in the oil-refining industry, performing industrial-sized capital investment planning (CIP) in this field is traditionally done using linear (LP) or nonlinear (NLP) models whereby a gamut of scenarios are generated and manually searched to make expand and/or install decisions.
Additional file 4: Table S3 shows the number of LD expanded models that were generated and tested for each of the original SNP-SNP interactions.
For each patient, iPSCs would be generated, expanded and (re differentiated to the type of cells most affected in the disease of interest - for example, motor neurons for amyotrophic lateral sclerosis (ALS) or spinal muscular atrophy (SMA) - and to those most commonly affected by drug side effects (cardiac myocytes and hepatocytes).
Layer VI (TBR1+), the deepest and first layer to be generated, was significantly expanded in thickness and cellularity (Fig. 4A,B).
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