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The freeform surface can then be further optimized through feedback modifications.
Compare to other conventional loss models, results showed that the Kacker & Okapuu model predicted the closest values to the CFD simulation results thus it can be used in the preliminary design phase of small axial turbine which can be further optimized through CFD modeling.
Note that this final filtering step could be further optimized through systematic comparative evaluation of ab initio models to RNA-Seq based gene models, but due to the limitations of time and data availability, we did not do this.
However, the rate of image acquisition at different depths can be further optimized through the technique of remote focusing, or changing the beam divergence to change the sample depth, introduced by Botcherby et al. [ 22 25].
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Parameters were further optimized through back analysis.
The parameters having significant effect were further optimized through a full factorial design.
The precoder is designed in two phases: first the intercell interference is removed by applying a set of distributed precoding vectors; then the system is further optimized through power allocation.
Herein we describe how the potency of a benzothiazole fragment hit was quickly improved based on structural information and how this early chemotype was further optimized through scaffold hopping.
Initial ABACUS designs were further optimized through screening additional FRET pairs and linkers.
In addition, we tested selected lactate dehydrogenases, some of which were further optimized through site-directed mutagenesis to improve the enzyme's affinity for the co-factor nicotinamide adenine dinucleotide phosphate (NADPH).
Log Po:w (=3.1) was further optimized through manual sensitivity analysis in the range of 3.0 4.0 to match predicted Vss (=1.49 l/kg) to reported Vss (=1.1 l/kg) and to improve Cmax prediction.
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