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The different abilities of Erlotinib and Gefitinib should be further established, as they might require dose adjustments or different treatment durations.
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Though most of the medals won by California breweries ended up in San Diego or the Bay Area, the Central Coast, traditionally wine country, was further established as a hotbed of beer making, with nine medals split between Figueroa Mountain Brewing in Buellton and Firestone Walker Brewing in Paso Robles.
The antagonistic effects of these E2F1 mutants were further established at the transcriptional level, as their overexpression significantly reduced TGF β-induced Caspase 7 and Smac/DIABLO mRNA levels.
However, the clinical utility of TRX has to be further established [ 40], as does the mechanistic explanation linking increased TRX levels with the biological disorders occurring after CA and post-cardiac arrest syndrome.
The long-term efficacy as well as the effectiveness of an intensive lifestyle intervention needs to be further established.
The potential utility of MRS as a screening instrument to be administered by paramedical workers should be further established.
Once this was corrected, the relatedness between HEAT and ARM repeats became immediately apparent (see also Fig. 2), as has been further established by the comparative analysis of Andrade et al [3].
Their potential as anticancer agents has been further established by in vivo studies, as these peptides have been shown to induce regression of primary tumors [ 8, 9] and prevent metastases [ 10- 13].
Overall results indicate that B. subtilis GRSW2-B1 has potential to be engineered and further established as a genetic host for bioproduction of butanol.
Therefore, B. subtilis GRSW2-B1 is markedly attractive to be further engineered and established as a genetic host for bioproduction of butanol.
This needs to be further explored as a longitudinal study to establish causal links.
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