Sentence examples for be further downregulated from inspiring English sources
For example, miR-204 was reported to be downregulated in primary RCCs and was found to be further downregulated in the current analysis.
This effect could be further downregulated by co-stimulation with both compression for C48 hours and 1400 W in peptide treated constructs (P < 0.01).
We discovered that the selenite-induced decrease of nuclear IKK alpha was inhibited along with enhanced expression of survivin-2B, whereas cytoplasmic IKK alpha was further downregulated.
At this time point, Smad7 mRNA declined compared to time zero, and was further significantly downregulated in the presence of HBR (Figure 1D).
ENST00000480739 expression was further significantly downregulated in PDAC patients with lymph node metastasis, which indicated that ENST00000480739 might have an important role in PDAC metastasis.
Interestingly, DAPK1 had no effect on the NF light chain (NF-L) but significantly downregulated WWOX protein levels (data not shown), which remains to be further elucidated.
In RA, angiogenesis may be further promoted via activation of Mφ by advanced glycation end products, whereas thrombospondin-2 seems to downregulate angiogenesis.
Also by downregulating the level of the proapoptotic Bcl-2 family member, bax, radiotherapy-induced apoptosis will be further inhibited.
Gene expressions using qRT PCR confirmed higher expressions of Cu/Zn SOD transcripts in both mutants and the absence of Fe SOD in sodPv 1 and Mn SOD in sodPv 2. In 50 μM arsenic, Cu/Zn SODs genes were further upregulated but other isoforms downregulated in the two mutants, maintaining SOD activity in its control level.
The abilities of DX-1 to induce apoptosis and to downregulate c-FLIP were further investigated in three additional leukemia cell lines.
The effect of FAS inhibitor on cancer is further verified by RNA interference to downregulate FAS in prostate and breast cancer cells, which induces apoptosis (De Schrijver et al, 2003; Bandyopadhyay et al, 2006).
