Sentence examples for be functionally significant in from inspiring English sources

Interestingly, the codon 16, but not codon 27, polymorphism has been reported to be functionally significant in females, in which it influences the sensitivity of the B2-adrenoceptor to agonists.3 However, this has not been studied in males.

These results suggest that social motivation and conflict resolution tactics are associated with social complexity, and that these behavioural traits may be functionally significant in the evolution and maintenance of sociality.

RING finger protein 13 (RNF13) is a newly identified E3 ligase reported to be functionally significant in the regulation of cancer development, muscle cell growth, and neuronal development.

This loop turns out to be functionally significant in the lens, and there is evidence that it began small and was accentuated by gradual selection as the crystallin took on its new visual function (Sweeney et al. 2007).

Although the IR also contains mucin-type O-linked glycans attached to six Ser/Tre residues located in the N-terminal portion of the β chain, a recent study suggested that O-linked glycosylation is unlikely to be functionally significant in the IR family [89].

This polymorphism had been proved to be functionally significant in individual variability of EGF expression.

The changes in histone H2A-PTMs when induced upon AT1R activation are functionally significant in altering the expression of genes.

There is also disagreement among studies as to which Notch receptors and target genes are functionally significant in OSA.

This indicates that neurogenesis is functionally significant in human disease and involved in the progression of breast cancer.

We clearly demonstrate in this paper that the changes in the proteins that we tested are functionally significant in metastasis in the systems analyzed.

While these structural differences are functionally significant in nature, difference in shapes of the two sterol skeletons was not commented on by the authors.