Sentence examples for be functionally significant as from inspiring English sources

This malleable tethering of the JM to the C-helix is likely to be functionally significant, as this may provide a framework for the JM and the activating monomer to dynamically control C-helix movement [11], [12].

The mtDNA depletion in MEFs and embryonic tissues was revealed to be functionally significant, as it resulted in reduction of steady state levels of mtDNA-encoded proteins, multiple respiratory chain deficiencies, and cellular respiration defects.

This regulated restructuring of mitochondria is functionally significant as disruption of these processes has negative effects on overall cellular function.

That increased beta2 subunit expression in sensory neurons after nerve injury is functionally significant, as demonstrated by our finding that the development of mechanical allodynia-like behavior in the SNI model is attenuated in beta2 subunit null mutant mice.

Importantly we demonstrate that this matrix protein structure is functionally significant as inhibitors of collagen synthesis block network formation.

This reduction is functionally significant, as PICH siRNA does not abolish SAC activity in a cell line that harbors a bacterial artificial chromosome driving the expression of murine Mad2.

An implication of these findings is that the brain preferentially simulates past or future experiences that are deemed to be functionally significant, such as those associated with reward.

CIs of these variants including the tRNAAla 5601C>T and tRNALeu CUN) 12280A>G were <70% CI, which was below the threshold level to be functionally significant in terms of mitochondrial physiology, as proposed by Wallace.

But this question remains unanswered, and the possibility that the number of cells produced is not large enough to be functionally significant has serious implications for popular claims, such as that exercise can improve memory, and also for the new view of the brain that has been adopted so quickly.

Though we cannot exclude indirect binding, the interaction of UNC-45 and UFD-2, two non-sarcomeric proteins, could be functionally significant.

This loop turns out to be functionally significant in the lens, and there is evidence that it began small and was accentuated by gradual selection as the crystallin took on its new visual function (Sweeney et al. 2007).