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This therefore highlights that ethnicity is a critical factor in the distribution of allelic frequencies, and may be functionally relevant in determining p53 function.
Analysis of colorectal cancer data sets suggests that this regulatory relationship may be functionally relevant in tumors with a normally functioning Ras pathway.
Also, PPC and MFG ceased to be functionally relevant in the same time window.
In fact, Prep1 is the first homeodomain protein whose translational repression activity may be functionally relevant in vivo in mammals.
Splice isoforms may be functionally relevant in disease or may act as biomarkers - indicators of normal or altered biological processes or pharmacological response to a therapeutic intervention [5].
In light of these observations, it is possible that a spacer of 24 bases might be functionally relevant in Arabidopsis.
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We next recapitulated the steps of melanoma progression through functional assays to determine whether TGF-β-induced transcription is functionally relevant in migration and invasion.
These studies provide support to the idea that the functioning of the larval cerebellum is analogous to its function in the adult and that the activity patterns we recorded are functionally relevant in the larva and in the adult.
Thus, further studies are necessary to test whether the Diva/Harakiri complex is functionally relevant in apoptosis.
Evidence does exist to suggest that relative specificity is functionally relevant in complex biochemical systems.
We demonstrate by specific knock-down experiments that EZH2 overexpression is functionally relevant in BRCA1-deficient breast cancer cells.
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