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PRR14 was reported to be functionally related with lamin A/C, which is implicated in myogenesis.
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Extracted total cyclic visibility components were functionally related with the corresponding components associated with PM2.5 load and meteorological variables.
The various degrees of interactive effects due to the surface ribs, side-profile leakage flows and streamwise weakened coolant flow are functionally related with Reynolds number (Re) and channel length-to-gap ratio (L/B), which unravel the considerable impacts on local and spatially averaged heat transfers over the rib-roughened fin surfaces.
Notably, in all cases, the number of gene pairs that exhibit high correlation scores and are functionally related with high probability, is small.
Analysis had indicated that the PLK1 plays important roles in tumorigenesis since it is functionally related with cell cycle.
Both proteins recognize interstitial cells (Ito cells) in the liver as well (Schmid et al. 1994; Theilig et al. 2001) and are functionally related with regulation of hemodynamic parameters (Le Hir and Kaissling 1993).
Often, co-expressed genes within a cluster are expected to be functionally related to genes with a similar expression pattern.
Fifteen CNV-loci were previously reported to be functionally related to or be associated with the investigated diseases (Table S2).
Modules of co-expressed genes likely to be functionally related were identified and correlated with BMI, plasma levels of glucose, insulin, HbA1c, triglycerides, non-esterified fatty acids, ALAT, ASAT, C-reactive protein, and LDL- and HDL cholesterol.
SWI/SNF and MYC are known to be functionally related, since MYC physically interacts with the SWI/SNF component, INI1 (Cheng et al, 1999), and BRG1 is required to repress the MYC-target, cad (Pal et al, 2003).
The key idea here is that if two genes share many regulatory elements, they are likely to be functionally related, and would share more edges with a reference network (see Data sources), which also captures functional relevance of genes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com