Sentence examples for be functionally important for from inspiring English sources

Occludin (60kDa), a tetraspan integral membrane protein, was the first TJ-specific protein identified [ 12, 13] in epithelial cells and shown to be functionally important for barrier function [ 14].

MiR-378 has been shown to function as an oncogene-like miRNA (Lee et al, 2007), to be functionally important for c-Myc-driven transformation (Feng et al, 2011) and to correlate with progression of human breast cancer (Eichner et al, 2010).

The Leu62 was shown to be functionally important for human Pol ι [42].

These proteins across the malarial species contain positional conservation of the tryptophan residues which could be functionally important for the parasite.

Thus, cystatin C may be functionally important for cells to maintain normal behaviour, which is in concordance with our present results that PC3 cells overexpressing cystatin C via transient transfection displayed less invasive phenotypes.

These motifs are likely to be functionally important for cuticle formation because they 1) derive from conserved orthologous blocks, 2) occur in different protein families known to be involved in cuticle (e.g., Tweedles, CPRs, CPFs, A. gambiae CPLC Gs or cuticle-associated processes (Dusky/Miniature), and 3) have conserved tyrosines.

Whether this substitution from a polar to a nonpolar amino acid is functionally important for MutL activity and function remains to be investigated.

Here, we use three homologues from a test family common to bioinformatics the LacI/GalR transcription repressors to test a common assumption: If a position is functionally important for one family member, it has similar importance in all homologues.

Lagace, D. C. et al. Adult hippocampal neurogenesis is functionally important for stress-induced social avoidance.

Data-driven statistical models calculated from the phosphorylation signatures successfully classified infected and uninfected cells and further identified signals that were functionally important for regulating cell death.

Using reverse genetics, the researchers will knock out specific genes to determine whether those genes are functionally important for the symbiosis, Harrison said.