Sentence examples for be functionally impaired in from inspiring English sources
However, studies have shown that CD152 may be functionally impaired in SLE, perhaps as a result of αCD152 autoantibodies [ 28].
In contrast, the 4 bp 5′ deletion characteristic of D2 alleles appears to be functionally impaired in reporter gene transfection studies.
Put simply, we postulate that CNS cells will display a senescent phenotype that is physiologically similar to cells that have undergone replicative senescence, and be functionally impaired in a way that leads to neuronal dysfunction and degeneration.
However, it was recently shown that although the frequencies of NK cells in blood do not differ from healthy controls, stimulated blood NK cells from NSCLC patients with advanced disease had a reduced granzyme B and perforin A expression, lower production of IFN-γ, and decreased cytotoxic function indicating that these cells are functionally impaired in comparison with healthy controls [ 14, 15].
Blair, P. A. et al. CD19CD24 hi CD38 hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic Lupus Erythematosus patients.
Blair, P. A. et al. CD19+CD24hiCD38hi B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic lupus erythematosus patients.
Viewed as a network disorder, mTLE has been found that the widespread brain regions are functionally impaired in addition to the mesial temporal lobe.
The explanation could be that the pRb2 pathway is functionally impaired in BL, expression being deregulated along the cell cycle or the protein accumulating due to inhibited degradation.
There is evidence to suggest that the incretin system is functionally impaired in people with T2D, although this is not universally observed [ 27- 31].
He is functionally impaired in all instrumental activities of daily living as well as in some basic activities of daily living.
Indeed, it has been demonstrated before that Tregs are functionally impaired in AAV and fail to suppress effector T cells [ 13, 14, 28].
