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Notably, pathways related to tumor angiogenesis and chemotaxis could be functionally different in these two patient groups.
Particularly, pathways related to chemotaxis, tumor angiogenesis, and immunobiology could be functionally different in the two patient groups.
Instead, a distinct pattern was observed which denotes biological processes including endoplasmic reticulum-associated degradation and chemotaxis in the tumor epithelium and angiogenesis in the tumor stroma that could be functionally different in African-American and European-American breast tumors (Figure 2).
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Radcliffe, P. A., Garcia, M. A. & Toda, T. The cofactor-dependent pathways for α- and β-tubulins in microtubule biogenesis are functionally different in fission yeast.
The experiments using an in vitro approach demonstrated that the DC subsets were functionally different in directing BCG antigen-specific T cells.
While basal BECN1 expression levels are comparable in sensitive and resistant cells (not shown), we could not exclude the possibility that its role is functionally different in these cellular contexts.
Whatever the explanation, these experiments showed that the two isoforms are functionally different in vivo.
Our results reveal that ROCK1 and ROCK2 are functionally different in regulating stress-induced actin cytoskeleton reorganization and cell detachment.
Upon adrenergic stimulation, monocytes differentiate into mature macrophages [ 12] that are functionally different in their cytokine response [ 13].
The results from this manuscript suggest that FFA activates a Ca2+ channel that is functionally different in human podocytes than in human glomerular endothelial cells.
This discrepancy could indicate that US2 is functionally different in the context of HCMV infection when compared with selective US2 expression systems.
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