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However, they do not appear to be functionally complex, as they have fewer recognized domains per gene than the rest of the genome.
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Heart valves are functionally complex, making surgical repair difficult.
As with the E. coli system, the B. subtilis Tat components have been shown to form two types of complexes; a TatC-containing complex that we assume to be functionally analogous to the TatABC complex, and a separate TatA complex.
Biochemical and genetic studies have identified that PcG complexes can be functionally separated into at least two distinct complexes: an initiation complex, PRC2, and a maintenance complex, PRC1.
In our analysis, we concluded that Rb may be functionally inactivated in UM as a result of cyclin/cdk complex phosphorylation that blocks its tumor suppressor activity.
Lipases and CESs are functionally related as well.
Both frames are functionally identical, as far as I could tell.
Given that protein complexes are molecular groups of proteins that work together as "protein machines" for common biological functions, we may expect the protein complexes to be functionally and structurally cohesive substructures in the binary PPI networks [ 14].
They have to be functionally equivalent campuses.
Of those, we found 65 associations with GWAS traits and provide examples in which genes implicated by expression are functionally validated as being relevant for complex traits.
Purified recombinant subunit IV is functionally active as it can restore the bc1 complex activity from the three-subunit core complex to the same level as that of wild-type or complement complex.
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