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Our analysis (see Figure 1, Cluster III) clearly shows that cluster III enzymes among enzymes of validated function are most closely related to salicylate 5-hydroxylases, however representatives of this cluster need to be functionally characterized to allow any clear functional assignment.
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Several antisense RNAs have been functionally characterized to date, including those involved in X-inactivation, genomic imprinting and clonal gene expression [4], [13].
To this end, we monitored the acetylation of histone H3 at the IL-12p40 promoter between position −121 to −131 (a region that has been functionally characterized to be important for IL-12 expression) [28], by chromatin immunoprecipitation (ChIP) and protein expression by ELISA.
None of these proteins have been functionally characterized to date.
No tick thyropins have been functionally characterized to date.
However, very few RBPs have been functionally characterized to date in the human parasite Plasmodium falciparum.
The other sequences, from rice, sorghum and millet have not been functionally characterized to date.
This enzyme is functionally characterized to hydroxylate medium-chain saturated fatty acids [ 53].
PRPS1 variants were functionally characterized to assess their impact on the enzyme activity, and detailed neurological evaluation was performed in order to refine genotype/phenotype correlations.
and sequences that are functionally characterized to some degree retain the name they were given in the paper in which they were identified.
Within plants only four members have been functionally characterized to any degree, and these studies show the importance of each member in essential cation accumulation, partitioning, and tolerance.
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