Moreover, LNP may be functionalized to reach target cells, and they may be used to combine RNAi molecules with conventional drug substances to reduce resistance or improve efficiency.
This is especially true in biological imaging mainly because the fluorophores can be functionalized to specific biological targets and because the signal from the fluorescence can be easily separated from the excitation light.
A powerful feature of the AFM is that the cantilever tip can be functionalized to react very specifically with a target molecule.
Biological studies showed that the C3 hydroxyl group has to be functionalized to ensure potency.
Once this is demonstrated, the SLBs can be functionalized to specific analyses for selective biosensor applications.
Furthermore, MSC can be functionalized with targeting moieties to augment their homing toward therapeutic sites using enzymatic modification, chemical conjugation, or non-covalent interactions.
However, as a PEG-coated nanoparticle, the porphysome platform can easily be functionalized with targeting ligands, for targets such as PSMA, EpCAM, or VEGFR.
Mesoporous silica could perform better than generic activated carbon since the silica surface could be functionalized for target specific adsorption.
The nanodiamond arrays were functionalized with lysozyme to target a certain biomolecule or protein specifically.
Following docking investigations, based on theoretical models of truncated SK2 and SK3 channels, the benzyl side chain of N-methyl-laudanosine (NML) was functionalized in order to target this specific amino-acid residues.
