HS2, a classical enhancer located in LCR, appears to be functional in erythroid cells at both embryonic and adult developmental stages, suggesting its crucial roles in the activation of globin genes in erythroid cells throughout ontogenesis [ 16].
To determine whether Arch is functional in Xenopus embryonic cells, we first examined Arch expression.
Recent studies have reported that phage integrases, such as ΦC31, R4 and TP901-1, were functional in the mammalian embryonic environment and had the potential for creation of transgenic animals and modification of the mammalian genome in vivo [26], [54], [55].
Lu SJ, Li F, Yin H, Feng Q, Kimbrel EA, Hahm E, Thon JN, Wang W, Italiano JE, Cho J, Lanza R. Platelets generated from human embryonic stem cells are functional in vitro and in the microcirculation of living mice.
Although Psc and Su z 2 have been shown to be functional homologs in that complex [37], an embryonic Su z 2-PRC1 complex may be targeted differently than a PRC1 complex containing Psc, and therefore potentially remove other components of the PRC1 complex from the dmyc locus.
Most were detected in embryonic tissues.
The tracks that were in process were in embryonic form, but he sensed their promise.
In the chick embryo, the onset of sympathetic cardiac innervation occurs at about embryonic day (ED) 9 and this system is functional by ED16 [ 8].
Analysis of these modifications suggests that many enhancers and super-enhancers functional in embryonic and adult tissues are already specified in sperm.
Pathway analysis revealed functional overlaps that have previously been shown to be involved in embryonic heart development.
