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An important challenge brought to chemical engineering by new emerging technologies, in particular then by nano- and biotechnologies, is to deal with complex systems that cannot be dealt with and cannot be fully understood on a single scale.
Although the detailed mechanism has yet to be fully understood on how high levels of ARA induces apoptosis, it is clear that if the metabolic pathways that consume ARA (and hence lower its level) are coordinately activated, tumour growth is then promoted [ 59] through apoptotic escape [ 60].
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None of the systems are fully understood on a mechanistic level.
Pathological processes cannot be fully understood based on the change in expression of individual genes alone since various factors act in concert in the development of specific diseases in the body.
Although the exact mechanism that links abnormal 5-HT neurotransmission to the manifestation of head pain has yet to be fully understood, a deficit on 5-HT descending pain inhibitory system is still probably today the most implicated in migraine pathophysiology.
Although the events that doomed the space shuttle Columbia may never be fully understood, investigators have focused on damage to thermal tiles inaccessible to the astronauts.
Because of this evidence of commonality, we believe non-food cravings cannot be fully understood by focusing solely on geophagy and therefore strongly encourage researchers to study other pica substances as well.
The clinical implications of these findings appear not to be fully understood and more data on the issue are necessary before conclusions can be drawn.
Although the empirical evidence points to higher post-merger prices and costs, the full impact of mergers on social welfare cannot be fully understood enough without considering their impact on quality.
The question of whether Wagner's music ought to be played in Israel cannot be fully understood rationally ["A Cultural Disconnect on Wagner" by Anthony Tommasini, Aug. 5].
(Even his popular work on the connection between Puritanism and the development of capitalism in the West cannot be fully understood without reference to his work on comparative institutions e.g., his studies of Asiatic religions and ancient Judaism).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com