Sentence examples for be fully established but from inspiring English sources
However, the causal relevance of many predictive biomarkers of CVD has yet to be fully established, but this may not necessarily be required for risk prediction.
The importance of PTEN as a phosphatidylinositol phospholipid-directed phosphatase, and antagonist of PI3K signalling, is well established; however, there are additional features of the PTEN molecule for which the functional significance remains to be fully established, but which may exert regulatory influence.
Estimates of M could be obtained with tagging studies or from age composition data (i.e. catch curves) in areas where lionfish are fully established but removal efforts have not occurred (i.e. total mortality = natural mortality).
Protection from diabetes after B 9-23/IFA immunisation cannot be achieved once diabetes is fully established, but can be achieved at most prediabetic stages of the disease.
The safety and efficacy of long-term device placement in humans has not been fully established, but in terms of effectiveness and applicability, these preliminary results are promising.
The mechanism by which corticosteroids might induce GI bleeding or perforation has not been fully established, but corticosteroids may impair tissue repair, thus leading to delayed wound healing.
The impact of ABPM and HABP parameters on TOD occurrence has not been fully established, but there are studies relating BP variability and night-time elevation to the presence of TOD.
The causal relationship has not been fully established, but the rather high prevalence of 37% of patients experiencing severe pain in the first week identifies a need to treat acute postsurgical pain more aggressively, regardless of the possibility of increased risk of persistent pain.
