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This model is consistent with an immunomodulatory role for LcrV: released LcrV would be free to diffuse away and have a broadly local or even a systemic effect during an infection process.
Similarly, a model might assume that only receptors within the contact area were immobilized, so that all receptors outside the contact area would be free to diffuse to the contact area.
Locally produced glucocorticoids will be free to diffuse into surrounding tissues.
If cobinamide is not physically trapped, it will be free to diffuse out of the pores even if the silicon matrix has not degraded.
However, in vivo the released calcium may be free to diffuse into the vast volume of the interstitial fluid without inducing vast toxicity to the macrophages themselves and to the surrounding cells.
Similar(55)
The free-water method eliminates partial volume with water molecules that are free to diffuse in the extracellular space, providing better estimates of diffusivities within the tissue [ 41].
These metabolites were free to diffuse in the cell and the cell membrane was permeable to allow diffusion of these metabolites between the cell and external solution.
This latter non-aggregating fragment is free to diffuse within the ECM and is rapidly lost into the synovial fluid.
The wellbore pressure is free to diffuse into the surrounding formation when there is no mudcake on the wellbore wall (Figs. 2, 6).
As can be seen in the mechanism shown in Figure 7, these excited states, i.e., (Ti3+-O−)*, contain the photogenerated electron and hole which are more localized on neighboring atoms [19, 20] and are closer than in bulk semiconductors, in which the charge carriers are free to diffuse.
After release, Syto 9 is free to diffuse into the core where its fluorescence increases upon binding DNA and RNA.
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