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A full description of the methods used can be found in Brain Donation in Normal Aging Procedures, Motivations, and Donor Characteristics from the Biologically Resilient Adults in Neurological Studies (BRAiNS) Project [621].
Since sexual orientation (i.e. sexual attraction to members of the opposite-sex or the same-sex) has also been related to prenatal androgenization [12], [13], we were interested if effects of sexual orientation could be found in brain morphology.
In addition, it has been shown that Vpr can be found in brain section of HAND patients, specifically in astrocytes and neurons [36] and neuronal cell death was observed in these patients, concomitantly with the presence of Vpr protein and transcripts [37].
Although expression of insulin I gene is restricted to rodent beta cells, InsII mRNA can also be found in brain, thymus, fetal liver and yolk sac [ 29– 31].
Interestingly, UBQLN2 pathology could also be found in brain and spinal cord tissue of ALS or FTLD patients without mutated a UBQLN2 gene (Deng et al., 2011).
– We know that gut bacteria (e.g. in Vijay-Kumar et al. 2010 Science, and numerous subsequent studies that should also be cited) can affect behavior, so it is not necessary that microbial differences would be found in brain tissue itself as proposed by the authors.
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Some overlapping findings were found in brain areas putatively important in AN, such as the insula.
Moreover, chronotropic cells were found in brain stems implied in sleep and cardiac regulations.
Viral sequences and proteins were found in brain macrophage/microglia cells and these cells were reported to be activated.
Infected phagocytes were found in brain and lung tissue samples from AIDS patients, indicating the brain infection might be caused by the phagocytes, the scientists wrote.
In research published in the Proceedings of the National Academy of Sciences, Kumar's lab microfabricated channels with a stiffness comparable to what is found in brain tissue.
More suggestions(15)
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