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I wasn't sure we could have en election that wouldn't be fixed, that wouldn't be rigged, that wouldn't be stolen by Karl Rove, as the previous one was..
"The system is broke and it needs to be fixed — that's the issue," Johnston said.
A useful analogy to describe this phenomenon is to compare a DNA-binding transcription factor (e.g. CREB) to a plumber or handyman that takes a toolbox (i.e. coactivators such as CBP/p300 and CRTC) to all job sites (target genes), but it is the nature of the problem to be "fixed" that determines which tools are required at each jobsite.
For example, in a murine line that has undergone 50 filial crossings, 99.998% of ancestral heterozygous loci should be fixed; that is, only approximately 2 in 100,000 of the originally heterozygous positions should remain heterozygous (Bailey 1978; Green 1981; Silver 1995; Peters 2007).
Where there is possible misunderstanding over which variables are to be fixed that information should be made explicit.
However, as Obama told Leno, the crisis wasn't created overnight and it won't be fixed that quickly either.
Similar(46)
One of the tougher things has been fixed, that is the game, in my opinion.
"Our company is fixing that error.
Sadly, it failed to work with Netflix, but Google has said it is fixing that issue.
Step by step, we're fixing that system," Obama said Thursday.
And we need to be fixing that.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com