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Their success suggests that it may be feasible to sequence the complete thylacine nuclear genome from museum specimens.
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In fact, the costs are so low that when one factors only the price to run the sequencer and the production of raw base reads, it is feasible to sequence megabases of DNA in thousands of individuals using a small number of sequencing runs.
Nonetheless, it is feasible to sequence targeted regions of the human genome in hundreds to thousands of individuals in an individual laboratory (Stratton, 2008).
We show that it is feasible to sequence a complete mitogenome, without PCR, from a snail that has been in 70% ethanol for eight years.
Now that you can sequence DNA increasingly cheaply and quickly, it is feasible to sequence the genomes of large numbers of autistic individuals, which almost certainly will uncover increasing numbers of rare, big-effect mutations that contribute to the disorder.
By using plasma samples, they showed that the method could identify mutations in TP53 at allelic frequencies of 2%to65%5%, thereby demonstrating that it is feasible to sequence large regions of circulating DNA by NGS [45].
These computational results suggest that it may be feasible to use multiple sequence alignments as an additional source of data when estimating the parameters of complex demographic models.
With the rapid accumulation of genomic information and resources such as genomic sequences [33], expression profiles and regulatory network [9], [34] [35], and mutant libraries [36] [40], it may be feasible to identify the candidate genes, by sequencing genotyping of a sufficiently large population.
We have shown that it is feasible to focus sequencing efforts on cases, at least at the outset.
Through multiplexing, it is feasible to generate deep sequencing data for 20 30 different bacteria in a single lane.
In this study, we have demonstrated that it is feasible to use Illumina sequencing to rapidly characterize multiple transcriptomes and compare their differences in an invasive non-model species.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com