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The transcription start site of the BMP-7 gene was found to be far upstream (764 bp) of the initiation ATG codon.
Because dendritic compartments often are distant from the nucleus, transcriptional control may be far upstream of the local events that regulate outgrowth and branching.
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"Down the line a bit, these sites will evolve to the point where they'll include players that are far upstream, like providers of sawmill equipment," he said.
A common convention in the industry is that station 0 is far upstream, station 1 is after the shock in the inlet (if there is one), station 2 is at inlet to the compressor (after the inlet/diffuser) and station 3 is after the compressor.
The condition x GSE>0 on the lunar orbit guarantees that the moon was exposed to the solar wind and was far upstream of the Earth's bow shock.
The third possibility is that the effects of Ot B on DAF-16 indirectly acted on proteins whose function is far upstream of the IIS signaling pathway, and simultaneously acted on protein in parallel to the IIS signaling pathway to regulate DAF-16.
For two of them, the position was far upstream (>5000 bp) of the annotated gene and thus not further investigated (OR10J7P and OR4C15).
The replication initiation protein is encoded on an unstable transcript with a weak promoter, PA, which is far upstream of PD, and protein C is encoded from transcripts that come from PB.
In human GK, the pancreatic exon 1 is located near the pancreatic (neuroendocrine) promoter, which is far upstream of the remainder of the coding region (exons 2 10) common to pancreatic and hepatic GK isoforms.
Because the qPCR returned a fold change of 0.5 when ZIC4, which is far upstream from exon 1 of PROS1, and when PRR15, which is on chromosome 7, were used for normalization, we conclude that the deletion in this family involves PROS1 and GPR15, including at least 20 confirmed genes in between.
Further study is needed to locate putative AREs expected to be found far upstream of the dolphin ferritin subunit genes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com