Sentence examples for be far downstream from inspiring English sources

First, the expression readout may be far downstream of the actual binding target and may lead to the pathway of action but not the direct protein target of the molecule.

In our opinion, the best phenotypes to examine in genetic analyses of renal aging should not be far downstream of the disease cascade; for example, examining nephrosclerotic changes in the early stage of their evolution and in the absence of confounding kidney disease could make detection of subtle changes possible even before they actually effect kidney function.

Our results showed that this location was far downstream from the flame anchoring zone, near the end of the recirculation zone.

You must exert prudence, however, before dashing off to the mailbox every other day, advises Yamamoto: "You should wait until you're far downstream in the negotiations" before penning notes and letters to current or future employers confirming negotiation details. "You have to know when to do these things".

Because elevated blood pressure is a systemic phenomenon, an emergent property that is far downstream from the function of individual genes, researchers are beginning to investigate the association of candidate genes with endophenotypes, or precursors to hypertension to increase the power of finding an association.

This latter STAT upregulation due to p65 overexpression is inconsistent with the structure of EGFR protein-protein interactions, in which p65 is far downstream of STAT.

The alpha lobes are far downstream from the calyx and the presumptive site of Drep2 action, and probably not important for STM.

Properties such as external stimuli or motor behaviors may be far "up", or "downstream" from their neural representations, depending on where in the brain data is recorded from.

Therefore, downstream households seemed to be far worse off and much more affected by hazards.

Such water management decisions should not be taken in isolation, as our study shows that the consequences of upstream measures and activities can be far-reaching in downstream areas.

As such, the introduction of Plk1 into adult myocytes could be too far downstream of this arrest, and therefore unable to bypass the other events that are necessary to occur before mitosis can take place.