N-Ethyl-N-nitrosourea (ENU) is the preferred mutagen in forward genetic screens, because it is extremely potent in the premeiotic male germ line, where it induces point mutations.
We additionally performed colony-formation assay showing that LCC was extremely potent in inhibiting C6 cell proliferation.
More importantly, the Vangl2Lp mutant protein is extremely potent in reducing Sdc4 levels in embryos as well as in cell culture.
The characterization of strain HS and related Sodalis-allied insect symbionts revealed that genome degeneration is extremely potent in the early stages of a symbiotic association.
BMPs are extremely potent in inducing myeloma cell death and thus, myeloma cells must have ways to escape the tumor suppressing effects of BMPs.
However, since rat UCMSCs were extremely potent in cell growth attenuation in simple in vitro cell culture studies where no immune cells or immunoglobulin were involved, it is likely that their in vivo effect is also independent of nonspecific immune surveillance induced by xenotransplantation.
Aminoheterocycles are found to be good urea surrogates, whereas bicyclic substituents on the C3 thio group were found to be extremely potent TrkA inhibitors in kinase and cell assays.
"These products, which can be extremely potent, have now been reported in virtually all European countries," it said.
The feeling of betrayal can be extremely potent.
The compound "seems to be extremely potent and active against even multidrug-resistant strains of P. falciparum," says David Fidock, a molecular parasitologist at the Albert Einstein College of Medicine in New York City.
