Sentence examples for be extremely difficult when from inspiring English sources

However, the removal of LPS is suggested to be extremely difficult when LPS is associated with protein to be purified [5] and has been an issue in pharmaceutical technology and science.

Treating rejection with steroids and other immune-suppressing drugs is extremely difficult when the transplant is an intestine.

This disorder may considerably restrict normal daily life and management is extremely difficult when treatment with oral H1 antihistamines and sun avoidance are ineffective.

It is extremely difficult when you hold a political appointment to search for a job it's just too much conflict of interest to negotiate with other entities.

Vettel said: "The pace was there but it was extremely difficult when I was close to Fernando and Jenson we seemed to lose a lot and not be able to stay close enough to try to something under braking.

"My education in Switzerland, and working in hotels there, gave me a good idea of what working in hospitality would be like, but dealing with the bureaucracy is extremely difficult when starting a business in India".

The series was extremely difficult when compared to other RPGs of the time, possibly because they were modeled after pen-and-paper role-playing games of similar difficulty.

This was extremely difficult when sharing with 3 other new mothers…".

Proving it is, um, is extremely difficult when there's so many other variables... so to do this work is [slight pause] almost a leap of faith, you know.

This process has proven to be extremely difficult, especially when analysts need to piece together information cues associated with various individuals, groups, events, and places, along with such items as communication and transportation logs[1].

The inclination to go into a shell in the face of problems or challenges creates an information vacuum that will be extremely difficult to bridge when you inevitably have to turn to your investors for help.