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Although a randomized trial represents the most rigorous method of evaluating a medical intervention, some interventions would be extremely difficult to evaluate using this study design.
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Improvements in the quality attributes of an RA (e.g., reuse, maintainability, security) are extremely difficult to evaluate in an analytic and quantitative fashion contrary to the efficacy of the business (e.g., sales) (Carriere et al. [2010]).
It is extremely difficult to evaluate the health of our workplace culture because objectionable conversations rarely occur in the open.
Complete response is seldom achieved via TACE and the presence of residual vital tumour is extremely difficult to evaluate.
It is extremely difficult to evaluate the accuracy of peak calling because of the lack of 'true' binding-site data.
The fact that it is extremely difficult to evaluate changes in the testicular function of men are emphasized and the extremely wide variability is pointed out.
Its value is extremely difficult to measure experimentally.
Unfortunately, parallaxes are extremely difficult to measure.
He'll be extremely difficult to contain.
"It will be extremely difficult to rescue people.
Rubisco appears to be extremely difficult to be engineered.
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