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Although, the experiment with REDD1 MEFs cannot be extrapolated to prostate cancer cells but using REDD1+/+ and REDD1−/− cells, modest resistance to cell death is observed in REDD1−/− cells as observed by cleaved-PARP and cell growth inhibition assays.
Although these data cannot be extrapolated to prostate cancer cells but it is evident from these experiments that MSeA is changing the redox state of cells in hypoxia and thereby increasing REDD1 and decreasing HIF-1 α.
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15 19 20 Hence, the results of this study can be extrapolated to other white European populations in which no widespread screening with prostate specific antigen tests is ongoing.
The same can be extrapolated to A-Rod.
The obtained results can be extrapolated to milling operation.
However, he cautioned that it was unclear whether the findings could be extrapolated to people.
Thus, these results can not be extrapolated to human heart.
This can be extrapolated to other parts of the world.
This can be extrapolated to the whole population of interest.
Barg's boardwalk example can be extrapolated to neighborhoods.
Also, our study results cannot be extrapolated to all IGRAs.
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