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Models are also helpful when results obtained in special laboratory or test structure experiments need to be extrapolated to more general situations (e.g. to real houses or even to other soil gas pollutants).
First, our findings cannot be extrapolated to more typical ICU samples with more cases of sepsis.
It is not clear whether they can be extrapolated to more advanced, larger lesions, including ischemic ones.
To ascertain that the biomarker findings are not biased by the SpA subtype and that the data can be extrapolated to more homogenous SpA study populations, we performed two additional sets of analysis.
The results of the present work suggest that the predictive property of percent area change, log healing rate, and ratio of log area can be extrapolated to more complicated, ischemic, larger, Wagner grade 3 or 4 ulcers.
It will interesting to evaluate the importance of individual Y-family polymerases in M1dG bypass in intact cells to determine if the results of in vitro experiments can be extrapolated to more complex cellular systems.
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Moreover, it is not clear if and how results obtained in laboratory strains, which are in general more ethanol sensitive, can be extrapolated to inherently more robust industrial strains [ 5].
It is expected that the results generated in this paper will be extrapolated to a more extensive study which may include the preceding and consequent activities of the power plant.
Finally, our scoring system was especially developed and validated for full hemodynamic evaluation at the bedside in critically ill patients and our results cannot be extrapolated to other more specific cardiological situations.
Whether these results can be extrapolated to situations more relevant to intensivists, such as the evaluation of critically ill patients with suspected ventilator-associated pneumonia,[ 10] remains to be seen.
Although major surgery is associated with significant impairment in both microvascular flow and tissue oxygenation [ 38], our data should not be extrapolated to other, more specific patient populations (with an increased intersubject variability) until further investigations are carried out.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com