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Exact(11)
First, our data demonstrate that the fitness cost of antibiotic resistance needs to be measured for each particular species of interest, and that the observations made in just one species cannot be extrapolated to another, since the genetic particularities might modulate the effects of bacterial fitness.
Thus, the findings obtained in one cell system cannot be extrapolated to another cell system.
Furthermore, African populations are known to exhibit greater genomic diversity when compared to white populations, and genetic findings in one population cannot necessarily be extrapolated to another [ 12].
They reminded that surrogacy depends upon the disease setting and the class of therapeutic agents and that validation cannot be extrapolated to another situation without further investigation.
However, they are subject to bias and therefore it is difficult to say whether results from one centre can be extrapolated to another centre (Expert Advisory Group on Cancer, 1995).
Whether or not our conclusions can directly be extrapolated to another AIMS - perhaps one based on keyboard or mouse-based entry - is unclear, although clearly the same testing protocol could be developed and used for other systems.
Similar(48)
Thus, utility and validation studies using only one CO device may potentially not be extrapolated to equivalency of using another similar device.
Studies documenting clinical benefit using catheter-derived estimates of cardiac output to drive resuscitation algorithms using one monitoring device cannot be extrapolated to similar utility by using another cardiac output monitoring device.
Another limitation is that the results cannot be extrapolated to newly arriving immigrant children (aged ≤18 yrs).
However, he cautioned that it was unclear whether the findings could be extrapolated to people.
An important question is the extent to which these latest findings can be extrapolated to the rest of the UK.
More suggestions(16)
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com