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Exact(15)
Therefore, even though laboratory results should not be extrapolated directly to field populations, our results suggest that reproductive success may be sensitive to noise pollution, potentially reducing fitness.
Thus, the in vitro results for B cells cannot be extrapolated directly to the results regarding T cell-independent antibody production in vivo.
Although results from mice cannot be extrapolated directly to humans, says Jerry Shay of the University of Texas Southwestern Medical Center in Dallas, the mice "really do show that telomere erosion can lead to things we see in [elderly] humans".
It is generally recognized that in vitro data cannot be extrapolated directly to in vivo or clinical settings, since assays in vitro assays do not account for tumour microenvironmental factors and the fact that tumors may contain clonogenic subpopulations of cells with different sensitivities to radiation or chemotherapeutic of interest (Hill and Robert 2008).
The role of GCAP1 in controlling cyclic nucleotide levels in photoreceptors has largely been elucidated using knock-out mice, but the disease pathology in these mice cannot be extrapolated directly to COD3 as this involves altered, rather than loss of, GCAP1 function.
Therefore these data can not be extrapolated directly to in vivo conditions.
Similar(45)
This research confirms that results from uncertainty analyses are often scale dependent and that results for one scale cannot directly be extrapolated to other scales.
As our model did not intend to reproduce the diffusion of ofloxacin in bacterial masses after a multiple human-like doses regimen, our results should not directly be extrapolated to what happens in patients.
One particular research group is studied, and therefore the findings cannot directly be extrapolated to other settings or generalised.
The present study is experimental and the results cannot directly be extrapolated to patients with lung injury and without use of inotropic drug and vasoactive drug administration.
Because of major differences in living conditions and environmental circumstances these study outcomes can not directly be extrapolated to industrialised countries.
More suggestions(15)
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