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Interestingly, all 9 novel miRNAs families showed extremely low expression levels, indicating that these miRNAs may only be expressed in certain physiology processes and may be the reason for why these miRNAs have not been detected until now.
For example, exons tagged by dplv nonsense mutations will be expressed in certain tissues, e.g. in tendon cells and in the trachea, the latter presumably necessary for viability, but not be present in dumpy messages in the developing wing.
However, these promoters have their own limitations as an RNAi/antisense-transgene driven by a regulated promoter will only be expressed in certain tissues/organs, at specific developmental stages, or in response to a unique chemical/physical signal but has no effect on the target gene in other relevant tissues/organs at certain important developmental stages [21].
In addition, some genes may not be expressed in certain tissues or developmental stages, leading to cases with undesirable amounts of missing data [ 9].
It should be noted that CD22 may be expressed in certain lung carcinomas, but this is still inconclusive, as the data have been conflicting [ 187, 188].
It is possible that the genes found not to be expressed in certain hosts may be expressed in those hosts under conditions other than those tested here.
Similar(52)
For example, there are many papers published using commercially available antibodies, all showing that a particular potassium channel is expressed in certain tissues.
Every family has its conflicts, and some are expressed in certain ways, others..
One similarity is that SNAI1 and SNAI2, like STAT3 and Leptin are expressed in certain cells of the TE in the expanded blastocyst, but not all.
However, not all SPI-3-associated responses will be useful and functional in all serovars because when some of them are expressed in certain strains, they could have a negative effect on pathogenic associated phenotypes.
Furthermore, meprin α is expressed in certain tumors such as colorectal cancer and, hence, might play a role in tumor cell migration and invasion, and cancer progression [13], [20].
More suggestions(15)
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be expressed in other
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be mitigated in certain
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be guaranteed in certain
be limited in certain
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be expressed in compact
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com