Genes with higher expression level divergence are more likely to be expressed at low levels [ 30].
A notable finding from this comparison is that whereas we identified the miR-200 family of miRNAs (miR-200a/b/c, miR-141 and miR-429) to be expressed at low levels in normal HOSE with highly increased expression in ovarian cancer, the study using E6/E7-immortalized HOSE did not find increased expression of miR-200 family miRNAs in ovarian cancer.
First, mCherry expression levels are controlled by endogenous target gene promoters that might be expressed at low levels during the early stages when we assessed the reporters.
They showed a slight increase in expression at PT1 stage and then a gradual decrease during later stages whereas miRNA34 and miR394_1 was found to be expressed at low level in all the stages with no variation in expression levels.
Johansson and his colleagues discovered that by mutating the structure of the bobby-pin-like RNA, they could cause the virulent protein to be expressed at low temperatures.
For the rice monocupins, subfamilies have members both with and without both UTRs, and thus it appears that there are members of each subfamily that may be expressed at low levels or not at all.
Tissue specific antigens, however, may be expressed at low levels and, therefore, may not be efficient at negative selection of lower affinity self-reactive clones [44].
Thus, it is critical for plants to keep FT to be expressed at low levels for preventing precocious flowering and for the regulation of FT by the photoperiods.
While Rgs9 is often thought to be specific to the basal ganglia, in mice it has been demonstrated to be expressed at low to moderate levels in the cortex [20], [31].
Second, the antibodies available to detect it had significantly lower affinity than the Tag antibody; third, related to the first, cyclin B1 was thought to be expressed at low levels compared to a stable, promiscuously expressed protein like Tag.
During tumor growth, PIK3CA may be expressed at low levels and p110α localizes mainly to the cytoplasm in cancer cells proliferating in proximity to vessels in a metabolically lush microenvironment.
