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Heterogeneity between trials was found in some analyses, which most likely reflects a sex interaction, but other causes of heterogeneity could not be explored owing to the scarcity of data.
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Although endothelial dysfunction might be present in many of the current animal models for ischemic diseases, the specific role of oxidative stress on therapeutic outcomes has rarely been explored owing to the confounding effects of different co-morbidities.
So far, the viscosity of fluids in nanoconfinement on a scale comparable to the molecular diameter is seldom explored owing to the extremely small scale on which the transport properties are difficult to be captured by experiments and the intrinsic limitations of the existing computational methods in the MD simulations [16 18].
Other approaches were not explored owing to limited material available but loss of expression with age has been reported previously using qRT PCR (Cronin et al, 2004).
The use of light as a stimulus to trigger drug release has been actively explored owing to its high spatiotemporal resolution.
The mussel-inspired polymeric hydrogels have been attractively explored owing to their self-repairing or adhesive property when the catechol groups of dopamine could chelate metal ions.
The possibility that more precise identification of patients who may benefit from IGF-IR targeting could be achieved by the use of algorithms that combines patient hormone levels and tumour characteristics remains open, but could not be explored in this study owing to small sample size.
Other puzzles are meant to be explored.
They are just waiting to be explored".
Improbabilities to be explored.
This possibility remains to be explored.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com