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Consequently, the agenda of maternal immunization with GBS vaccines aimed at either reducing maternal recto-anal colonization, or preventing disease in the newborns through transplacental antibody transfer, needs to be explored in settings with a high burden of GBS disease.
In the population-based cohorts, the contribution of genetic variants on lung function can be explored in settings other than chronic smoking.
As this was found in services making use of governmental guidelines, the use of such guidelines should be explored in settings where similar levels of diagnostic agreement have not been achieved.
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None-the-less, the findings provide an important introduction to this field of study and should be explored in other settings to determine if similar benefits of graduate-entry programmes can be identified over time and in different settings and the challenges identified are managed.
The use of hand-held centrifuges and battery-operated water-heaters should be explored in field settings to investigate whether, during epidemic conditions, they could serve as reliable alternatives to be used for CSF sample preparation prior to the Pastorex® test.
With associations between sex and drugs starting early (Table 2) interventions to address links between sex and substance use should also be explored in school settings.
Because 3D/spheroids represent a closer model to tumor biological complexity, these results suggest that this combined therapeutic option should be explored in clinical settings.
Furthermore, the provision of incentives should be explored in different settings if DARE becomes widely recommended as a routine part of HIV care as providing incentives has been found to be important for increasing uptake of other screening tests such as pap tests and mammograms [ 20].
Thus, although the activity of BAY 80-6946 certainly will have to be explored in additional settings, such as rationale-based combinations with targeted and chemo therapeutics, our data provide the first experimental evidence that such future studies are a worthwhile path to pursue.
However, such potential risk factors need to be explored in future outbreak settings.
This study shows a novel association between low SpO2 and increased CBFv, which should be explored in non-African settings.
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