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In addition, phosphoproteomic approaches can be exploited to monitor changes in phosphorylation events in order to characterize drug actions on cell signaling pathways and/or signaling cascades.
Furthermore, phosphoproteomic approaches can be exploited to monitor changes in phosphorylation events in order to characterize drug actions on cell signalling pathways and/or signalling cascades.
In this way, the high specificity of binding and ligand-mediated conformational changes in bPBPs can be exploited to monitor for the presence of a specific ligand.
We demonstrate that this sensor can be exploited to monitor Cdc42 nucleotide exchange and GTPase activity in a continuous, fluorescence assay.
The experiments illustrate how p-cyanoPhe can be exploited to monitor amyloid formation even in the presence of other amyloidogenic proteins.
This method illustrated how large amounts of MODIS images may be exploited to monitor flood dynamics with adequate spatial and temporal resolution and good accuracy, except during the flood rise due to cloud presence.
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Moreover, doxorubicin is a fluorescent molecule with a chromophore group composed of three planar and aromatic hydroxyanthraquinonic rings, and its intrinsic fluorescence is exploited to monitor its accumulation in living systems [6].
Here, the information on the charge state and on the atomic surrounding of the considered element provided by XAS was exploited to monitor the degree of occupancy of 5d states of Pt in the course of oxide formation and growth, and to elucidate the competing halide adsorption/desorption phenomena.
The ability to separate mononuclear from binuclear cells was exploited to monitor, by flow cytometry, the passage of fission yeast cells through mitosis.
This is a known phenomenon related to the influence of the folding intermediates of the payload on the folding of EGFP, and was exploited to monitor stability of the recombinant proteins in in vivo selection systems [12].
The rapid kinetics of DIFO−azide reactions were exploited to monitor the dynamics of cellular glycosylation during zebrafish embryo development.
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