Sentence examples for be exploited to inhibit from inspiring English sources
The ability of micelles, by manipulation of charge to repel ionic species, can be exploited to inhibit undesired reactions and thereby improve selectivity.
We demonstrate that the NEMO core domain is a dimer that binds two IKK fragments and identify energetic hot spots that can be exploited to inhibit IKK complex formation with a therapeutic agent.
Targeting of these pathways at multiple levels can be exploited to inhibit the process by which NE cells contribute to the progression of androgen-independent treatment-refractory PC.
These observations underscore the possibility that, once identified, endogenous ErbB antagonists might ultimately be exploited to inhibit tumour progression in patients.
We have focused our efforts in studying the mechanisms underlying metastasis in pancreatic adenocarcinoma, with the goal of rationally identifying molecular targets that can be exploited to inhibit this process.
In the future these properties may be exploited to inhibit oxidative phosphorylation in cancer cells which are particularly dependent on it, such as in prostate cancer [ 74], cancer cells with up-regulated OCT1 transporters, such in as ovarian cancer [ 61], or cancer cells with detrimental complex I mutations that render them hypersensitive to inhibitors [ 75].
More recently, this drug has been exploited to inhibit the growth of tumor stem cells and chemoresistant cancer cells [ 18– 20].
These parameters can thus be exploited to either inhibit or purposefully induce a collective detachment of sheet-like microtissues for the use in tissue engineering and regenerative therapies.
Recently, there have been suggestions that small structural differences between enolases could be exploited to selectively inhibit enolases from parasitic protozoa [6], [29].
Further molecular investigation uncovered novel links between cyclin D1b expression and elevated PARP activity and markers of genome instability, which could be exploited to effectively inhibit tumor cell growth.
Thus, fibrillin-1 and fibulin-5, but not elastin, can be exploited to enhance endothelial stability, and to inhibit SMC migration within vascular graft scaffolds.
