We propose that the different modes of membrane binding may be exploited in structure-based drug design efforts for cancer therapy.
Examples of the role of different interactions, as well as molecular flexibility, in ligand receptor binding are provided and of how understanding these interactions can be exploited in structure-based ligand design.
A number of molecular recognition features have been exploited in structure-based design of selective Cathepsin inhibitors.
Both Lm and D2 have strengths that can be exploited in studies of lung structure.
On the other hand, non-biomolecular strategies will allow the full gamut of synthetic chemistry to be exploited in the optimization of nanomaterial structure, function, and properties.
This allows for the preparation of norcaranes with different substitution patterns and defined relative stereochemistries, and could be exploited in the design of complex structures bearing this bicyclic moiety.
This special graph structure will be exploited in the proposed algorithm to efficiently solve the TARP.
On the other hand, this residual interference is actually discrete belonging to a finite alphabet and its structure can be exploited in the detection process.
It turns out that the modular structure can be exploited in such a situation, to split a high-dimensional problem into subproblems involving only lower-dimensional summary statistics.
This property can be exploited in the separation of molecules having linear structures from those having bulky structures.
The bottom-up structures can be exploited in nanobiotechnology by harnessing their built-in properties and combining them with new functional modules.
