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These sites can be exploited for structure-based inhibitor development.
Difference in the substrate specificity of the human and LDGLOI enzyme could be exploited for structure-based drug designing of selective inhibitors against the parasite.
The structures reported here elucidate the binding modes of these inhibitors to Chk2 and provide information that can be exploited for the structure-assisted design of novel chemotherapeutics.
Atomic resolution details may unravel mechanistic insights and reveal unique and novel protein features, as well as important protein protein and protein ligand interactions, which ultimately lead to a better understanding of M. tuberculosis biology and may be exploited for rational, structure-based therapeutics design.
The increasing availability of series of compounds annotated with biological properties can be exploited for building Quantitative Structure-Activity Relationship (QSAR) models.
This issue can be addressed by generating and analysing RILs, since they capture and stabilize a large number of recombination events, which can be exploited for the characterization of genome structure and recombination landscapes, as well as for quantitative trait locus (QTL) mapping.
The coaxial EHDA process can be exploited for preparing CF with tailored structures.
High etch selectivity can be exploited for the fabrication of MEMS structures using silicon dioxide as mask/structural layer.
The CNT array owns a forest-like structure that could be exploited for the deposition of a polymeric thin film acting as drug delivery device.
This restriction gives the quantization regions a certain structure that can be exploited for analytical tractability, at the cost of a small performance loss.
The approach that is proposed here will both reduce the complexity of the problem as well as provide models which have a circulant structure that can be exploited for control design.
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