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We review the evidence for these therapies and discuss new scientific findings that can be exploited for new therapeutic interventions.
This article surveys our understanding of transporters that are modulated by specific pathogens and the mechanism(s) involved, thereby illuminating targets that might be exploited for new therapeutic approaches.
So, extracts of TAE and DAE could be exploited for new potent antimicrobial agents.
Whereas the physiological activity of 27HC remains to be determined, its discovery highlights how cells have adopted mechanisms to allow the same receptor ligand complex to manifest different activities in different cells, and also how these processes can be exploited for new drug development.
Clearly, the poor survival of this group of patients emphasizes the importance of identifying molecular characteristics that might be exploited for new therapeutic strategies.
Analysis of the chitotriose/gp96 binding site on BAAV will lead to a better understanding of the transcytosis activity in the lifecycle of the AAVs and the potential to provide information that could be exploited for new applications of AAV gene transfer vectors, such as the engineering of vectors which could navigate the blood brain barrier.
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Based on the two program packages used, two different experiments were carried out, with the aim of identify batteries of models to be exploited for designing new cardioprotective agents from libraries of new chemical entities.
The structure of the N-terminal NadM domain may be exploited for designing new antitularemia therapeutics.
The fact that a design and optimization process like software development can be modeled on the large with the laws of statistical physics poses intriguing issues to software engineers, and could be exploited for finding new metrics and quality measures.
This phenomenon could be exploited for a new vibrotactile approach to friction perception; however, the principles behind it have yet to be explained.
We also validated our findings by applying RE to species of Virgibacillus, Gracibacillus and Geobacillus and can be exploited for describing new species [146].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com