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Hence, information on DNA-binding modes, as well as recognition and repair of DNA damage is discussed, since this information may be exploited for improved structure activity relationships.
The work easily extends to vector estimations, in which case spatial correlation can be exploited for improved performance.
More recently, Gough and colleagues reported thermolysin as a complementary tool to PK. Thermolysin destroys PrPC in ovine or bovine brain while leaving PrPSc in its full-length form, thereby allowing the N-terminal domain of PrPSc to be exploited for improved methods of prion-disease diagnosis [ 23] or prion-strain discrimination [ 24].
Given its role in the maintenance of genome stability, the synergy with KRAS mutations, and the clinical significance of altered expression, we propose that deficiencies in STAG2 represent a potential therapeutic vulnerability that can be exploited for improved treatment and possible prevention of PDA.
A fundamental goal of current studies is to identify those somatic events arising in the variable landscape of PDA genomes that can be exploited for improved clinical outcomes.
These studies suggest that there are common determinants for both dental and diabetes self-care that could be exploited for improved management of both conditions.
Similar(53)
ZFNs and TALENs produce 5′ overhangs that could potentially be exploited for improving incorporation, whereas Cas9 mainly produces blunt ends.
Thus considerable allelic variation present in these root genes can be exploited for improving maize root characteristics.
As Power and Energy become the limiting factors for computer designs and systems, the inherent fault tolerance in some applications can be exploited for improving efficiency of computer systems.
The present theory could be exploited for improving designs and performances of shear oscillators in fluids, and reciprocally for investigating fluid properties by using shear oscillatory probes such as atomic force microscope in shear-mode.
The model indeed provided the structural rationale for its interaction with ligands and the cofactor and revealed unique characteristics of its binding site which could be exploited for improving the specificity of the inhibitors.
More suggestions(15)
be targeted for improved
be formulated for improved
be optimized for improved
be selected for improved
be sandboxed for improved
be stabilized for improved
be designed for improved
be administered for improved
be explored for improved
be modulated for improved
be criticized for improved
be used for improved
be modified for improved
be tested for improved
be stored for improved
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