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This promoter trap strategy can be exploited for expression analysis and validation of drug targets deduced from various non conclusive strategies such as bioinformatic analysis and microarray.
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The advent of transcriptome sequencing has yielded a huge amount of transcribed sequence data, such as expressed sequence tags (ESTs) that can be exploited for gene expression profiling, genome annotation, comparative genomics and physical mapping.
Recent studies have shown that the Gram-positive bacterium Lactococcus lactis can be exploited for the expression of heterologous proteins; however, a versatile set of vectors suitable for inducible extracellular protein production and subsequent purification of the expressed proteins by immobilized metal affinity chromatography was so far lacking.
Further elucidating these cis regulatory regions in hyperaccumulators could enable the manipulation of HMA4 expression that may be exploited for use within crop systems to enhance Zn leaf accumulation for biofortification or phytoremediation strategies.
Below we highlight the utility of MozAtlas for identifying classes of gene with tissue or sex-biased expression that may be exploited for vector control.
Indeed, a major proportion of circulating tumor cells - probably generated by EMT - display combined expression of one or more EMT markers and ALDH-1 [ 36], suggesting that combining the ALDH-1 and CD44+/CD24-/low CD44+/CD24-/lowilexpressionexprofilesfor the isolation/detection of the highly tumayigenic subeexploited-associated breast CSCs.
As these connections are biologically relevant, we proposed that hubs could be exploited for creating a biologically relevant subnetwork of expression-active genes.
Microarray analysis methods produce large sets of gene expression data that can be exploited for novel insights into the fundamentals of molecular biology research.
As a rapid approach for gene discovery and analysis of gene expression and regulation, data can also be exploited for the development of functional genetic markers.
Although the perfect tumor-specific gene does not exist, the differences in gene expression between tumor and normal can be exploited for therapeutic or diagnostic purposes.
These tumours have high expression of somatostatin receptors (sstr), which can be exploited for diagnostic and therapeutic purposes (Nilsson et al, 1998).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com