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Thus, apoptotic pathways might be significantly altered in cancer cells relative to untransformed cells, and these differences might present a therapeutic window that can be exploited for development of cancer drugs.
Our recent discovery of a Src inhibitor, RACK1, which works both to inhibit growth (by suppressing Src activity at G1 and mitotic checkpoints) and to induce death of colon cells, could be exploited for development of new and more powerful and selective strategies for treatment of human colon cancer.
These results suggest that the root aqueous extract of C. edulis contain potent anti-viral agents against HSVs that can be exploited for development of an alternative remedy for HSV infections [50, 51].
DMC1 recombination requires hydrolysis of ATP, a feature that can be exploited for development of small molecule inhibitors.
Further structural and functional characterization of the unique and novel fungal aaRSs is required before they can be exploited for development of anti-fungal compounds.
Presence of the core RNAi components in the A. apis genome and RdRP homolog can be exploited for development of an RNAi-based control strategy of this bee pathogen [ 36].
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Patterns of differentially serum protein expression between CCA and BBTD patients were exploited for development of diagnostic or prognostic tool for this type of cancer.
These properties can be exploited for the development of flow directing materials, e.g. wound dressings that prevent development of stress concentrators while augmenting transport of pharmaceuticals to the wound site, as well as transport of drainage away from the wound site, via convective flow.
Ragon Institute researchers develop a method to identify weak points in viral proteins that could be exploited for vaccine development.
These characteristics could also be exploited for the development of another electrostatic separation process.
We suggest that grafting of metal nanoparticles on GFs could be exploited for the development of efficient field emitters.
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