Typically about 10% of the estimated heritability has been explained for most complex traits when applying GWAS; indeed, the strongest obesity-associated variants in FTO and MC4R only account for less than 2% of the variance in adult BMI, with the combined results of all obesity GWAS loci still accounting for only a very small fraction of the heritability of BMI.
Apart from the presence of shared environmental factors, this familial aggregation can be explained for the most part by an important hereditary component in the pathogenesis of the disease.
Despite some recent tinkering, the system remains hugely biased against savers and in favour of borrowers and intermediaries such as banks and securities firms.Savers have little choice over where to invest their money; for reasons that will be explained later, most of them put it on deposit at the bank or, increasingly, the post office.
If spontaneously shown (i.e., without any evidence for learning), EP may be explained most easily (and cognitively least demanding) by avoidance of the wrong option [4].
The strong positive direct effect of the herbicide-induced increase of graminoids on leafhopper species richness can be explained by the preference for graminoids displayed by most leafhopper species found in our study (see Additional file 4: Figure S3 and Additional file 1: Table S4) which is in accordance with other studies [ 37].
This similarity may be explained by the practice that the treatment for most patients in the CA group was integrated with that of the VA group as soon as possible.
It is important that the risk level be explained in a readily comprehensible way and for most patients this might be in terms of the expected excess number of breast cancers for every 100 years of follow-up as judged from individual risk factors.
Lack of follow-up data could for the most part be explained by the fact that Family Group Conferences are frequently utilized to prepare a family for the expiration of the Supervision Order, when the youngster turns 18-years-old.
Most of them will be explained below.
The reasons for administering the measure were explained to most patients (90.3%), and in the vast majority of cases (91.9%) the episode was recorded in the case history, although a report was sent to the judicial authorities in only 126 cases (60.3%).
