However, the occurrence in Sweden of ESBL, nor pAmpC, producing E. coli cannot be explained by antibiotic usage because this usage is very limited.
This could be explained by the usage of a threaded Kirschner wire that has its medial extremity threaded that can provide higher stability of the construct, especially to telescopic forces.
Unconditional RF1 removal can be explained by the usage of UAG in E. coli genome.
Given that the signature "pervades both coding and noncoding DNA," its uniformity throughout the genome "cannot be explained by preferential codon usage [ 9]." The converse proposition, that codon usage is explained by dinucleotide relative abundance, is hardly more defensible, since dinucleotide frequencies do not determine trinucleotide frequencies [ 11].
A declining prevalence of K103N/S and Y181C/I overtime may be explained by the reduced usage of EFV and NVP which preferentially select for such mutations [ 24].
Overall, the effect of CMV serostatus on BK viral infection is unlikely a chance finding and cannot be explained by the different usage of CMV prophylaxis with valganciclovir given the low incidence of BK in D-R patients.
As a result of detailed analysis of the relationships between patterns of the changes in dN/ dS ratio and the variations of codon usage bias for each gene, we found that only nine rate changes could be explained by changes in codon usage bias in the specific lineage; these genes were YDR490C, YEL036C, YER174C, YGL141W, YIR003W, YJL061W, YLR298C, YMR301C and YPR113W.
Unlike the K27M mutation of glioblastoma, nearly all of the K36M mutations were found in H3F3B (∼90 %) rather than in H3F3A, which cannot be explained by differences in codon usage between H3F3A and H3F3B.
The different phenotypes observed in these two mouse models could be explained by possible alternative exon usage in the latter, although the expression of FGFR2 IIIb) was reported normal at least between E12.5 and E14.5.
