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The observation that defensins are localised to lymphocyte nuclei [ 28], could similarly be explained by unspecific binding to shuttle proteins.
This may be explained by unspecific protein binding leading to the pool of bound metabolites, which increases over time due to intracellular accumulation of metabolites.
It may also be explained by unspecific cell residence in the vascular bed of the BM, caused by capillary congestion from the heavy cell load or immunocomplex formation.
However, the findings by Choubey et al. [ 78] can also be explained by unspecific inhibitor (analog of miltefosin) binding, resulting in the inhibition of both choline kinase and phosphoethanolamine methyltransferase [ 77].
The abnormal curve observed in Kit A was repeated and confirmed and could possibly be explained by unspecific factors in the sera which interfered with the binding of the antibodies.
This might be explained by unspecific packaging of cytosolic eYFP into budding virus particles, since we observed that in this case release was also influenced by the presence of a functional HIV late domain (data not shown).
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This unrealistically high recovery efficiency might be explained by some unspecific hybridization of the oligonucleotide probes (Bouvier and del Giorgio, 2003).
The mobilization of small amounts of As and Fe from FeAsS by the cells being in decline phase can be explained by an unspecific dissolution of arsenopyrite by metabolites (e.g., ligands and organic acids) released during cell lysis.
Importantly, the anti-tumour effect could not be explained by an unspecific systemic inflammation, as plasma levels of TNF α remained undetectable in all animals, while positive controls (LPS injection) yielded values of 1098±261 pg ml−1 (not shown).
This trend change may be explained by the assumed unspecific high number of false-positive miRNA target site predictions that can be partly filtered out by filtering by their RNA duplex energy values [11], [14], [30].
The lack of a training effect might be explained by the use of an unspecific task (that is nevertheless representative of "real-life" training situations) and/or by insufficient duration/intensity to induce long-lasting changes.
More suggestions(15)
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be influenced by unspecific
be explained by environmental
be affected by unspecific
be explained by prolonged
be triggered by unspecific
be explained by bureaucratic
be explained by political
be explained by mutual
be explained by widespread
be explained by different
be explained by several
be explained by insufficient
be caused by unspecific
be sequestered by unspecific
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